Epstein–Barr virus latent genes

The latent herpes simplex virus.

Expression of Epstein-Barr virus encoded latent genes in nasal T cell lymphomas.

AIMS To determine the expression of Epstein-Barr (EB) virus encoded latent genes in nasal T-cell lymphomas in The Netherlands. METHODS Seven europid (Dutch) cases of nasal T cell lymphoma were investigated for the presence of EB virus by RNA in situ hybridisation (EBER). The expression of the EB virus encoded genes BARF0, EBNA1, EBNA2, LMP1, LMP2A, LMP2B, and ZEBRA was studied at the mRNA lev...

Expression of bcl-2 in Burkitt's lymphoma cell lines: induction by latent Epstein-Barr virus genes.

The bcl-2 oncogene blocks programmed cell death (apoptosis). Epstein-Barr virus (EBV) can immortalize B lymphocytes into continuously growing lymphoblastoid cell lines (LCL) by the coordinate expression of at least 9 latent genes (EBV nuclear antigen [EBNA] 1-6, latent membrane protein [LMP], and terminal proteins [TP] 1 and 2). We analyzed transcription and expression of bcl-2 and latent EBV g...

The expression and function of Epstein-Barr virus encoded latent genes.

The association of Epstein-Barr virus (EBV) with various malignancies is well established but the pattern of EBV latent gene expression in these different tumours is variable, reflecting distinct aspects of the virus-cell interaction. These different forms of EBV latency are associated with phenotypic variation and highlight the influence of EBV latent proteins on cell growth and survival. The ...

The Major Sources of Genetic Differentiation Among Apricot Latent Virus (ApLV) Isolates

Background and Aims: Apricot latent virus (ApLV) is a species within Foveavirus genus (Betaflexiviridae family, Tymovirales order). Phylogenetic analyses using different ORFs nucleotide sequences divided most ApLV isolates into two clusters. However, there is little data about the sources of genetic differentiation among ApLV isolates. Materials and Methods: Partial coat protein (CP) sequences...